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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN1
All Species:
19.39
Human Site:
S578
Identified Species:
32.82
UniProt:
Q16512
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16512
NP_002732.3
942
103932
S578
P
S
S
P
S
S
L
S
S
P
I
Q
E
S
T
Chimpanzee
Pan troglodytes
XP_512443
1169
127241
S805
P
S
S
P
S
S
L
S
S
P
L
Q
E
S
T
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
Y630
P
P
K
P
P
R
L
Y
L
P
Q
E
P
T
F
Dog
Lupus familis
XP_542019
1076
118222
S711
P
S
S
P
S
S
L
S
S
P
I
Q
E
T
T
Cat
Felis silvestris
Mouse
Mus musculus
P70268
946
104392
S581
P
S
T
S
C
S
L
S
S
P
T
H
E
S
T
Rat
Rattus norvegicus
Q63433
946
104449
S581
P
S
T
S
C
S
L
S
S
P
T
H
E
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
L618
P
P
R
L
F
L
P
L
E
P
V
A
G
D
S
Chicken
Gallus gallus
XP_422357
1013
114806
P602
E
L
E
P
E
P
P
P
A
P
P
R
A
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689331
948
107057
Q587
D
I
S
T
P
E
R
Q
P
S
T
E
P
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
N304
K
C
S
L
L
D
F
N
F
I
K
V
L
G
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
D377
G
G
T
L
S
I
H
D
F
T
F
M
K
V
L
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
R438
P
L
T
P
P
A
A
R
S
S
P
P
P
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
T763
F
R
D
M
N
S
E
T
F
Q
I
E
Q
D
H
Red Bread Mold
Neurospora crassa
P87253
1142
127954
D736
P
A
D
Y
A
N
I
D
A
Y
S
S
P
Q
A
Conservation
Percent
Protein Identity:
100
79.3
38.7
83
N.A.
91.6
91.9
N.A.
42.2
57.6
N.A.
66.7
N.A.
29
N.A.
27.8
48.5
Protein Similarity:
100
79.9
52.6
84.3
N.A.
94.7
94.6
N.A.
56.1
72.1
N.A.
79.5
N.A.
42.8
N.A.
43.4
61.7
P-Site Identity:
100
93.3
26.6
93.3
N.A.
66.6
66.6
N.A.
13.3
20
N.A.
6.6
N.A.
6.6
N.A.
6.6
26.6
P-Site Similarity:
100
100
40
100
N.A.
73.3
73.3
N.A.
26.6
40
N.A.
20
N.A.
13.3
N.A.
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.8
28.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.4
45.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
8
0
15
0
0
8
8
0
8
% A
% Cys:
0
8
0
0
15
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
15
0
0
8
0
15
0
0
0
0
0
15
0
% D
% Glu:
8
0
8
0
8
8
8
0
8
0
0
22
36
0
0
% E
% Phe:
8
0
0
0
8
0
8
0
22
0
8
0
0
0
8
% F
% Gly:
8
8
0
0
0
0
0
0
0
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
15
0
0
8
% H
% Ile:
0
8
0
0
0
8
8
0
0
8
22
0
0
0
0
% I
% Lys:
8
0
8
0
0
0
0
0
0
0
8
0
8
0
8
% K
% Leu:
0
15
0
22
8
8
43
8
8
0
8
0
8
8
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
8
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
65
15
0
43
22
8
15
8
8
58
15
8
29
0
8
% P
% Gln:
0
0
0
0
0
0
0
8
0
8
8
22
8
8
0
% Q
% Arg:
0
8
8
0
0
8
8
8
0
0
0
8
0
0
0
% R
% Ser:
0
36
36
15
29
43
0
36
43
15
8
8
0
43
22
% S
% Thr:
0
0
29
8
0
0
0
8
0
8
22
0
0
15
36
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
8
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _